1.活動主題：專題演講: Hybrid structural biology approaches targeting phosphatase-substrate complexes for new cancer drug design strategy

Reversible phosphorylation is an essential post-translational modification in the regulation of numerous cellular activities. This fundamental mechanism is precisely controlled by protein kinases, protein phosphatases and thousands of their phosphoproteins in any given cells. Excessed or inadequate dephosphorylation of substrates may occur under various disease conditions due to abnormal expression, activation or inactivation of phosphatases. In this project we have focused on PTPN3, a member of membrane-associated protein tyrosine phosphatase, and two of its specific substrates, mitogen-activated protein kinase 12 (MAPK12/p38γ) and epidermal growth factor (EGFR) pathway substrate 15 (Eps15).

        2. 參加對象：高雄醫學大學全校師生

        3. 參與人數：50人    

        4. 活動時間：104年4月8日(星期三)  10:00 ~ 11:30

        5. 活動地點：勵學大樓3樓半 視聽中心

        6. 活動議程：     

9:45 ~ 10:00  報到

10:00 ~ 10:10 開場致詞

10:10 ~ 11:20 專題演講

11:20 ~ 11:30  Q＆A時間

         7.講員：Kevin Kai-En Chen陳愷(忄恩)博士

         8.報名網址:https://docs.google.com/forms/d/1hY6CzA4j9S5dOvQb2qh0UC30aXl9YEEb6Ys2hMsIIoU/edit

         9.聯絡人:陳冠璇    分機:2559#11   e-mail:khchen@kmu.edu.tw

◎該活動教師成長計分（研究成長類別）成長（1）分

◎現場紙本簽到退

歡迎大家踴躍參加！！

附件下載：

File	File size	Last modified
陳愷(忄恩) 博士合照	5134 kB	2015-04-24